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203 The N-terminus contains the major nuclear hormone receptor-interacting motif (LXXLL), which facilitates ligand-dependent interactions with different transcription factors like ER, 204 PPAR, 205 RXR, 206 glucocorticoid receptor and HNF4

Glutathione also plays a critical role in the bodys defense system against oxidative stress by acting directly to neutralize free radicals, as well as by maintaining the activity of vitamins C and E

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Biochemistry 32, 46934697