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But several factors work against this natural recovery process, including age (collagen production drops roughly 1% per year after age 20), the amount of weight lost (more than 50 pounds creates significantly more laxity), how long the excess weight was carried, sun damage history, smoking, genetics, and the speed at which the weight came off

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Exposure to 250 MeV protons induces dose-dependent apoptosis in the murine small intestine, with notable hypersensitivity observed at doses as low as 0.1 Gy