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Finally, at the moment of writing, one human clinical study reported that patients with lung cancer and T2D showed a significantly improved prognosis when cotreated with a combination of sodium-glucose cotransporter 2 inhibitors and GLP-1RAs (68)

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4.4 Coronary heart disease Excessive ROS accumulation has been shown to upset the equilibrium between the oxidation and antioxidant systems, leading to oxidative stress, which is a major factor in the development of coronary heart disease