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Always involve your prescribing physician in any decision to pause medication

See all patient experiences switching from Tirzepatide to Retatrutide Why Consider Switching There are a few practical reasons you might be thinking about switching from tirzepatide to retatrutide

A Phase 2 clinical trial published in the New England Journal of Medicine in 2023 reported mean body weight reductions of approximately 24% at 48 weeks at the highest studied dose

Retatrutide has demonstrated a generally favorable safety profile across Phase 2 and Phase 3 clinical trials

In principle, there could be weak or strong evidence, either in favor of or against, the hypothesis that incretin-based medications can increase the risk for pancreatic, (medullary) thyroid, or other carcinomas