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Differently from GSH, which enters the cells directly, SAG is more stable in blood plasma and, once entered into cell cytoplasm, is converted by cytoplasmatic thioesterases to GSH

Higashi Y, Sukhanov S, Anwar A, Shai SY, Delafontaine P: IGF-1, oxidative stress and atheroprotection

DSIP was isolated by Schoenenberger and Monnier, who reported recovering it from the cerebral venous blood of rabbits during electrically induced sleep and published the characterisation in 1977

Strandwitz P (2018) Neurotransmitter modulation by the gut microbiota

Indirect effects on sleep can occur with any medication that causes significant metabolic or physiological changes