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In preclinical tests, the most commonly noted side effect was mild local irritation at the injection site

Individuals with a personal history of medullary thyroid carcinoma or family history of multiple endocrine neoplasia type 2 (MEN2) should not use GLP-1 medications, as the theoretical riskthough unproven in humansremains medically inadvisable given disease severity

A review of therapeutic options for managing the metabolic aspects of polycystic ovary syndrome

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It's temporary per session but cumulative with regular treatment.