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The most common side effects of Mounjaro are related to the gastrointestinal system, which can include: Lack of appetite Nausea Diarrhea Vomiting Stomach pain Constipation Gas Fast heart rate Injection site reactions In rare cases, Mounjaro can cause severe side effects, such as: Serious allergic reactions Pancreatitis (inflamed pancreas) Changes in vision Hypoglycemia (low blood sugar) Severe stomach and intestine problems Severe gallbladder problems Risk of thyroid cancer Acute kidney injury Dr