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Keshavanath, P

Taken together, Akkermansia muciniphila may exert a double-edged sword effect on the homeostasis of the gut-joint axis through changes in its abundance: at moderate levels, it enhances intestinal barrier function and inhibits inflammation, while dysbiosis (either excessive or insufficient abundance) exacerbates the pathological progression of OA by disrupting mucus layer integrity and promoting toxin translocation

MT1 is a linear 13-amino acid peptide acting as a selective MC1R agonist, studied primarily for melanogenesis pathway research

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