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Genetic variants in GLP1R and GIPR receptors, for example, affect how strongly your body responds to these medications

Poster presented at: ObesityWeek 2025

Clinical research on GLP-1 receptor agonists has shown that some patients develop deficiencies in B12 and folate within 612 months of consistent use, especially if dietary intake is already marginal

Severe abdominal pain or persistent vomiting during any GLP-1 receptor agonist treatment requires urgent medical attention via 999 or A&E

SURMOUNT trials demonstrated mean weight loss of 2027% at the 15 mg dose, with some patients experiencing greater metabolic improvements in lipid profiles and insulin sensitivity compared to GLP-1-only therapy