2008 May 1;1783 (5):71327
Similarly, branched-chain amino acids, such as leucine, isoleucine, and valine, are catabolized in skeletal muscle to produce acetyl-CoA and succinyl-CoA, which enter the TCA cycle and contribute to ATP production
The use of lactate for energy has been proposed to occur within the mitochondria where it can be oxidized to pyruvate by mitochondrial LDH which localizes to the inner mitochondrial membrane
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Common side effects reported by the Mayo Clinic include: Diarrhea Headache Nausea If these side effects become severe or troublesome, let your healthcare provider know immediately