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May 22, 2024 Update: U.S

Long-term success with GLP-1s requires a commitment to lifestyle changes, including regular exercise and a nutritious diet

Their argument hinges on the perils of the unregulated marketplace, that many Americans are now injecting themselves with unvetted substances sourced from overseas

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Used together in appropriately selected women, HRT (started within the timing window) and a GLP-1 agonist may offer additive cardiovascular protection through complementary mechanisms: estrogen via favorable lipid effects and vascular function, GLP-1 agonists via blood pressure reduction, weight loss, and direct cardiac effects [36]