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The skin barrier problem This is the fundamental issue that makes current GLP-1 patches implausible as weight loss tools

Glucagon-like peptide-1 receptor agonists (GLP-1RAs) are a promising therapeutic option for people with arthritis and obesity or type 2 diabetes mellitus owing to their pleiotropic effects, including weight loss, improved survival and reduced risk of major cardiovascular and renal events

Thus, although notable advancements have been made in scaling current production processes, industrial investments into novel biopharmaceutical strategies are urgently needed

Patients switching between semaglutide and tirzepatide should understand the conversion protocols involved