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Diagnosis is made with a biopsy showing spindle cells with wavy nuclei resembling fibrosarcoma

Sci Total Environ 650:27052716

Those USP chapters were substantially revised in 2023, tightening requirements for beyond-use dating, environmental monitoring, and personnel training

The same issue comes up with Telmisartan - I love it when my patient has a bit of hypertension - as this gives me the opportunity to Rx a drug with great data for longevity, whereas my patients who are ideal body weight and have a SBP of 105 I cant recommend these therapies

However, the metabolism of phenytoin may be saturated based on its zero-order kinetics, so phenytoin metabolism cannot increase any higher