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Although no significant change was observed in the bone formation marker P1NP, the semaglutide group showed a significant increase in the bone resorption marker CTX and a reduction in areal BMD at both the lumbar spine and total hip

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A study showed that in adults with type 2 diabetes and chronic kidney disease, Ozempic lowers the risk of worsening kidney disease, kidney failure (end-stage kidney disease), and death due to cardiovascular disease