Semaglutide Protects against 6-OHDA Toxicity by Enhancing Autophagy and Inhibiting Oxidative Stress
b , Left, volcano plot showing relative fold change (log 2 ) in lipid abundance versus log 10 (adjusted P value) of Mito-IP samples from Mito-tag HEK293T cells compared to those from control-tag HEK293T cells
Semaglutide, a GLP-1 receptor agonist originally designed for type 2 diabetes, has demonstrated significant effects on lipid metabolism beyond weight reduction
Finally, disproportionality analysis based on FAERS showed neither causality nor quantified risk due to the lack of pharmacological mechanism study but only showed an evaluation of the signal strength, which was just a statistical association ( Conclusion We explored the relationship between GLP-1 RAs and gastrointestinal AEs from various perspectives and quantified the potential risks based on a comprehensive and systematic retrospective analysis of the FAERS database
[DOI] [PMC free article] [PubMed] [Google Scholar] 83.Li X., Wang T., Zhou B., Gao W., Cao J., Huang L
