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Thus, while compensatory central gain increases are well-established in hearing loss, their specific contribution to tinnituswhether increased, decreased, or absentremains an open question requiring further investigation with well-controlled, hearing-matched designs (Sedley, 2019
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Proteinprotein interaction network analysis highlights TNF and AKT1 as central regulatory nodes, suggesting that Tripterygium may modulate key inflammatory and fibrotic signaling pathways (217)
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