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Recent studies have implicated neuroinflammatory changes as being crucial in the development of ASD, with evidence of significant microglial activation and increased production of inflammatory cytokines and chemokines, including Interferon- (IFN-), IL-1, IL-6, and TNF- (159, 160)

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Coronary and arterial plaque (atherosclerosis) develops gradually as cholesterol particles such as LDL in the blood are "lipid oxidized" and damage the blood vessels' lining, forming a plaque

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