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GLP-1 medicines have been used to treat type 2 diabetes (T2D) for more than 18 years, and for the treatment of obesity for 8 years

I have seen more significant [gastrointestinal] side effects with oral semaglutide than with injectable, Moreno said, noting that he wonders what differences in side effects may occur when using such high doses of semaglutide compared with [the] injectable dose. In the trial, Novo Nordisk said, the vast majority of side effects of oral semaglutide were mild to moderate and diminished over time. All GLP-1 medications are associated with side effects including nausea, vomiting and abdominal pain, although not all patients experience them

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Early diagnosis of diabetic neuropathy is possible if regular screening for this complication is conducted using modern diagnostic methods