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O-class GSTs were able to modulate ryanodine receptor calcium release channels in cardiac muscle due to structural similarities to Chloride Intracellular Channel Proteins (CLIC) [219]

This system is crucial for the maintenance of homeostasis and survival of the organism and due to its wide distribution it regulates several physiological responses such as the transmission of nociception, cardiovascular activity and the circadian cycle

MSCs are an example of a normal cell type that releases Exos, which have shown specific therapeutic advantages for different diseases [78], such as myocardial ischemia [79, 80], neurological disorders [81], and skeletal diseases [82]

Retinoids: Powerhouses like retinol and tretinoin are fantastic for the skin's appearance, but they can sometimes cause sensitivity

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