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Kocher, A., Bohnert, L., Schiborr, C

Patient Variation in Pernicious Anaemia, as Shown in a Clinical Trial of Cyanocobalamin, Hydroxocobalamin and CyanocobalaminZinc Tannate Variation between patients makes it impossible to anticipate the duration of effect of a single injection of one of these drugs in any patient

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This is an unusual mechanism of drug interactions, since usually displacement from albumin will expose more drug to be metabolized (leading to re-equilibration)