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GHK-Cu and Gene Expression Research Research using the Broad Institutes Connectivity Map found that GHK is capable of up- and downregulating at least 4,000 human genes, with studies identifying 47 DNA repair genes stimulated and 5 suppressed findings that suggest a broad regulatory role at the genomic level

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By using arginine as the salt form, penta deca peptide arginate delivers both the active peptide and additional arginine to support nitric oxide production