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treated cells were incubated with JC-1 dye (5 g/mL) for 30 min at 37 C, followed by fluorescence detection using a fluorescence microscope, where the red/green fluorescence ratio was calculated to quantify mitochondrial polarization status, as a higher ratio indicates healthier mitochondrial function while a lower ratio suggests mitochondrial depolarization and dysfunction

Hypotension and orthostatic hypotension were more frequently seen in patients on concomitant antihypertensive therapy

But it could also be pretty expensive for the government