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Furthermore, heritability estimates range from 30 to 40% (Girgenti et al., 2021) with genome-wide studies implicating immune-linked loci such as ANKRD55 among others (Stein et al., 2016

Psychiatry 12, 669089

Sample Collection Collect from the infant's heel according to the NCCLS Approved Standard LA4-A2 "Blood Collection on Filter Paper for neonatal Screening Programs" Second edition (1992) NCCLS, Villanova, PA After the sample is taken and the blood has dried, the cards must be stored at 2-8oC

Regular review ensures that treatment remains appropriate, effective, and safe throughout the duration of therapy