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In the body, IGF-1 plays a role in: Cellular repair Muscle tissue regeneration Collagen synthesis Metabolic signaling Because of its prolonged activity, IGF-1 LR3 dosing requires careful clinical oversight

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Prog Neuropsychopharmacol Biol Psychiatry (2010) 34:14.10.1016/j.pnpbp.2009.11.009 135 MasakiTChibaSYasudaTNoguchiHKakumaTWatanabeTet alInvolvement of hypothalamic histamine H1 receptor in the regulation of feeding rhythm and obesity