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10.1016/B978-012543590-1/50021-4 [DOI] [Google Scholar] 58.en G, Akbulut S, Karakse M

86 ShiB.Sepp-LorenzinoL.PriscoM.LinsleyP.DeangelisT.BasergaR

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GLP-1 agonists like semaglutide directly reduce appetite by slowing gastric emptying and signaling satiety centres in the hypothalamus, leading to spontaneous caloric reduction of 2030% in most patients