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[8] [9] Common Gastrointestinal Side Effects Explained Nausea, diarrhoea, vomiting, and constipation are the most common gastrointestinal side effects of retatrutide, reported in up to 60% of Phase 2 trial participants and increasing with higher doses

If you have recently started using Ozempic to manage your weight or blood sugar, you might be focused on common side effects like nausea or changes in appetite

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While weight loss amplifies these benefits, the medication's metabolic effects on insulin signaling occur independently, making it a treatment for PCOS pathophysiology rather than just a weight-loss tool