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475 Deletion of the ZIP2 gene notably intensified myocardial I/R injury, whereas upregulation of ZIP2 demonstrated the potential to mitigate I/R injury

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To further verify whether OGD treatment could cause endothelial cell senescence, -galactosidase (SA--gal) staining was performed on the endothelial cells treated with OGD

Recent evidence suggests that oxidative stress may also promote life expectancy [3, 4]