Vitamin C, D & E : These arent just vitamins, theyre co-antioxidants that recharge glutathione and reinforce your defense against UV-induced oxidative stress
These include people with inherited metabolic disorders, severe malnutrition, kidney disease requiring dialysis, liver disease, or gastrointestinal conditions that reduce nutrient absorption
An adaptive response typically will not have any evidence of pathological change in the liver
GSH deficiency results in the activation of von Willebrand Factor (Violi et al., 2017): notably, hypercoagulation is a prominent life-threatening complication in COVID-19 patients ( Notably, low GSH plasma levels have been identified along with three other clinical indicators (age, CD3 ratio, and total protein) as a predictor of the severe/critical symptoms of COVID-19 infected patients (Sun et al., 2020)
Once B12 supplementation is started, the improvement can be quite striking even within the first few weeks