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Those limitations are not technical footnotes

These medications are not licensed or recommended by NICE or the MHRA for managing elevated cortisol levels, and they should not be considered a treatment for Cushing's syndrome or other primary causes of hypercortisolism

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It has become highly discussed in the media due to the increase in it being prescribed to people whose weight is affecting their health, or who wish to lose weight and have found that diet and exercise alone hasnt been sufficient

A 2026 study in mice also ties GLP1 receptor agonist effectiveness for weight loss to the bodys ability to use fatty acids for energy