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GLP-1 medication changes may support long-term weight management Patients who switch obesity drugs after less than a year stay better engaged with their treatment, UTSW researchers find DALLAS March 10, 2026 Patients without diabetes who switched GLP-1 receptor agonist (GLP-1RA) drugs for overweight or obesity were more likely to stick with their treatment longer than those who didnt switch, according to a new study by UT Southwestern Medical Center researchers