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This leads to the accumulation of excess oxygen radicals, contributing to oxidative stress and further triggering CSD (44)

Treat patients with variants in POMC, PCSK1, or LEPR genes that are interpreted as pathogenic, likely pathogenic, or of uncertain significance (VUS) in the clinical context of the patient [see Clinical Studies (14.3, 14.4)]

In some contexts, it promotes tumor growth

According to researchers, these findings will encourage the experts and drug developers to take into account symptoms posted online by users

A small proportion of patients (5.3%) carried a type 1 diabetes mellitus diagnosis, likely reflecting off-label prescribing and/or coding imprecision