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Research & Development 2 min read Eli Lillys triple agonist retatrutide shows 28% weight-loss in key Phase-3 study According to the topline results of TRIUMPH-1 study, the once-weekly drug highest strength 12 mg helped patients to shed 28.3 per ent (31.9 kg) of their body weight, followed by 25.9 per cent and 19 per cent with the 9 mg and 4 mg dose respectively

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However, the larger ACT trial (n=2,308) did not confirm this benefit (ACT Investigators, Circulation, 2011) [68]