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While the agency has cited "significant safety risks" as the rationale behind this categorization, it has not divulged the specific methodology or details pertaining to the identified risks

Satb2 deletion decreased the energy metabolism of colonic epithelial cells by down-regulating the transcription of PPARG In further exploring how Satb2 contributes to intestinal mucosal repair, we initially hypothesized that its increased expression might promote the proliferation of colonic epithelial cells during the repair process following irradiation

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