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Veroniki AA, Jackson D, Viechtbauer W et al (2016) Methods to estimate the between-study variance and its uncertainty in meta-analysis

Studies have also demonstrated that these two compounds can work synergistically in certain situations, such as inhibiting the growth of vascular smooth muscle cells

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This does not mean that pigmentation on the side of the tongue is malignant - most of the time, it is not - but it does mean that pigmented lesions in this location should be evaluated with appropriate thoroughness

The end result should be a perfectly clear solution with no visible particles or cloudiness