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The proportion of MTC extracted using this operational definition was 0.5% of all cases of thyroid cancer, which is similar to the 0.6% reported in a survey on the status of thyroid cancer in Korea using the Korean National Cancer Center registry database, which contains histological information [21]

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The rate of thawing does not reverse the damage caused by ice crystal formation

Effective data-driven approaches include: Predictive analytics allow PBMs to intervene before high-cost specialty utilization becomes unmanaged spend Biosimilar opportunity identification requires drug-level data that most PBMs don't surface Claims patterns can reveal clinical gaps, adherence risks and cost optimization opportunities The next wave of specialty cost management will be driven by how well programs use data to act, not just report 2