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Premature assessmentsuch as evaluating efficacy after only 46 weeks on the initial 2.5 mg dosemay not reflect the medication's true potential at therapeutic doses

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This further reinforces the notion that cellulite and lipedema are clinically distinct entities.36 Histologically, cellulite-prone areas like the gluteal region show subcutaneous tissue organized into layers separated by fibrous septa, which are key to its pathogenesis

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