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It's crucial for individuals on GLP-1 therapy to focus on nutrient-dense foods that provide sustained energy, such as whole grains, lean proteins, and plenty of fruits and vegetables, to help mitigate these feelings of tiredness

This phenomenon, sometimes called tolerance or dose creep, is reported anecdotally with tirzepatide, though the clinical trial data does not show significant tolerance development at fixed doses over 72 weeks

Clinicians prescribing GLP-1s for obesity management should focus on and help mitigate these challenges by developing care plans that include thorough nutritional and lifestyle counseling before, during, and after the weight reduction period

Semaglutide results The STEP clinical trial program showed that patients on semaglutide 2.4 mg weekly lost an average of 15 to 17 percent of their body weight over 68 weeks

While surgery offers more dramatic results, Sofwave and Pure Impact provide non-invasive, low-downtime alternatives ideal for patients with mild to moderate laxity or those not ready for surgery