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Clayman, MD, FACS, FACE, senior author of the white paper, said in a release

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The STEP trials demonstrated that semaglutide produces weight loss averaging 1522% over 68 weeks, while the SURMOUNT trials showed tirzepatide achieves 2022% weight reduction

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Others, particularly those who lose weight very rapidly, may experience temporary irregularity, missed periods, or changes in flow

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