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Supplementary Figure 4 All-cause mortality(26weeks)

In DR, oxidative stress also influences DNA methylation [64], Aberrant methylation of key genes involved in the inflammatory response in the retina has been observed

However, a recent placebo-controlled study [13] demonstrated that the DPP-4 inhibitor vildagliptin significantly improved glycaemia (with a lower incidence of hypoglycaemia) in patients with type 2 diabetes with long-standing disease (~15 years) and poor glycaemic control (HbA 1c ~8.4% [68 mmol/mol]) on large doses of insulin (~80 units daily)

The Out-of-Bag (OOB) error rates were 0.062 for PWA conditions and 0.125 for PNA conditions, indicating robust model performance (Fig

For best results, use as directed and pair with a balanced nutrition and exercise plan