This compound is a well-known extremolyte a type of small organic molecule that can protect cells under extreme, virtually [un]inhabitable conditions.7 In addition to protecting the skin from intense stress, ectoine also appears to improve the stability of various peptides by strengthening their hydration shell.8 Some research suggests that GHK-Cu (the copper peptide used in most copper peptide products) may have insufficient stability and could be prone to decomposition by skin proteases.9 Theoretically, then, the inclusion of ectoine in Allies of Skin Copper Tripeptide & Ectoin Advanced Repair Serum might be able to promote better stability and efficacy of the peptide
Structural modifications, such as attaching a lipid chain to a lysine residue, can enhance the peptides effectiveness by prolonging its half-life and bioavailability through non-covalent interactions with albumin
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It also protects against glutamate excitotoxicity through calcium signaling and N -methyl-D-aspartate (NMDA) receptor activity [79]