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Notably, ingredients matter to consumers when it comes to skincare since 43% of consumers consider it an important factor when purchasing skincare products

Water-heavy gels without penetration aids deliver most GHK-Cu to the stratum corneum surface rather than viable epidermis and dermis

Feature selection was consistent across folds, with the same 12 metabolites repeatedly selected in more than 35 cross-validation folds, indicating stable model performance ( Figure 4F )

Therefore, more comparative studies examining the wound healing effects of GHK and larger peptides are needed to provide robust evidence on how peptide size and structural complexity influence therapeutic efficacy