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This review will focus on recent findings describing how different pathological states compromise BBB integrity, discuss current potential therapeutic approaches that have been explored for improving BBB integrity and slowing neurodegenerative disease pathologies, and the recent findings in microbial mediated modulation of the BBB

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In a parallel-arm, open-label human study, twelve healthy subjects ( n 6 per group) received a single oral dose of either LipoDuo or plain glutathione (1 g), and plasma glutathione levels were monitored over 24 h using LC-MS/MS

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