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Glucocorticoids impair peripheral glucose uptake and increase the availability of FFAs

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They have different mechanisms to influence organ-specific tropism via different signaling pathways, such as the chemokine pathway CXCL12/CXCR4 (161), integrin-mediated adhesion (163), and changes in the ECM and tumor cell extracellular vesicles to establish a pre-metastatic microenvironment (164, 165)

Reynaert NL

These findings suggest that GSH depletion occurs during and after mild COVID-19 infection and persists for at least 3 months, regardless of PCC status