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This secreted protein is identified as liver expressed antimicrobial peptide 2 (LEAP2)

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Semaglutide (Brand name Ozempic) is an injectable medication which, when used in combination with diet and exercise, helps with blood sugar control, appetite control, and potential weight loss

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The GLP-1 RAs are now generally recommended for second line therapy after metformin in many patients with T2DM (120), but the truth is that rather few patients actually use them