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Description

Lipophilicity: Compounds must balance water and fat solubility to navigate both the lipid-rich stratum corneum and the aqueous living epidermis beneath

and the present study

MOA: Suzetrigine blocks a pain-signaling sodium channel (NaV1.8) in peripheral nerves helping relieve pain without acting on opioid receptors

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Imagine designing a study around a compound that isn't even what you think it is