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Elevated NADH inhibits mitochondrial -oxidation and suppresses fatty acid synthesis, resulting in intracellular lipid accumulation (You and Arteel, 2019

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Furthermore, it highlights the importance of direct cardiovascular and metabolic actions beyond weight loss in mediating the positive outcomes observed with GLP-1RAs in clinical trials

154 In another animal model, supplementing virgin olive oil with lycopene had an additive beneficial effect on blood lipids and even resulted in a decrease in body weight gain