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Authors: We found that oral vitamin B 12 replacement at 1000 g daily was adequate to replace vitamin B 12 levels in patients with pernicious anemia

show that PLGA nanoparticles covalently coupled with the myelin proteolipid protein epitope PLP 139151 induce potent antigen-specific tolerance in the relapsing-remitting model, preventing and treating relapsing EAE through reduced CNS infiltration of Th1/Th17 cells and suppression of epitope spread (176)

These tests aim to clarify the acute, potentially toxic potential of the substances but do not address the impact of chronic exposure to low doses of the chemicals

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The nuclear factor-B (NF-B) pathway plays a central role in amplifying cellular inflammatory responses (Lawrence 2009)