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The process of selecting papers, data collection as well as the quality assessment was performed independently by two authors (A.S., G.R.), and all disagreements were resolved by the discussion with the third author (R.O)

Ipamorelin binds to ghrelin receptors in the brain, signaling the body to increase growth hormone release without significantly affecting other hormones such as cortisol or prolactin, unlike older GHRPs

This action helps restore proper capillary blood flow and oxygen delivery to oxygen-starved tissues, directly combating the physical fatigue associated with vascular inflammation

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The most commonly used dosage is 0.5 mg daily