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Bioorg Med Chem Lett 24:53575363 Bryant P, Pabst M, Badescu G, Bird M, McDowell W, Jamieson E, Swierkosz J, Jurlewicz K, Tommasi R, Henseleit K et al (2015) In vitro and in vivo evaluation of cysteine rebridged trastuzumabMMAE antibody drug conjugates with defined drug-to-antibody ratios