Peroxisome proliferator-activated receptors: experimental targeting for the treatment of inflammatory bowel diseases
Quickstart Highlights Dihexa (also written PNB-0408
USP2 WT transfection promoted TGF1-induced nuclear localization of SMAD3, and increased SMAD3-mediated transcriptional activity, the protein level of TGFBR1 , and the mRNA level of TGF signaling target genes ( COL1A1, COL1A2, SERPINE1 , and SMAD7 ), while USP2 K447R abolished these effects (Fig
Cell Metabolism 15(6):838-847. [doi.org]
2022 Jul;37(1-3):171-183 PMID: 34806400 PMCID: PMC9293684 SCOPUS ID: 2-s2.0-85132339483 11/23/2021 (Singh B, Kosuru R, Lakshmikanthan S, Sorci-Thomas MG, Zhang DX, Sparapani R, Vasquez-Vivar J, Chrzanowska M.) Arterioscler Thromb Vasc Biol